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H. Jack West, MD
Medical Director, Thoracic Oncology Program, Swedish Cancer Institute, Seattle, WA; CEO, Global Resource for Advancing Cancer Education (GRACE)

FDA Approves Keytruda For Advanced Non-Small Cell Lung Cancer

(FDA.gov) Oct 2, 2015 - The U.S. Food and Drug Administration today granted accelerated approval for Keytruda (pembrolizumab) to treat patients with advanced (metastatic) non-small cell lung cancer (NSCLC) whose disease has progressed after other treatments and with tumors that express a protein called PD-L1.

Commentary: This is clearly an important approval, but with nivolumab already approved for squamous NSCLC and listed as a recommended...

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Roche Says Data Shows Cotellic Combination Therapy Effective

(Reuters) Oct 6, 2015 - Swiss drugmaker Roche said final survival data from a Phase III clinical trial showed the Cotellic drug used in combination with Zelboraf helped people with previously untreated BRAF V600 mutation-positive advanced melanoma live significantly longer compared to Zelboraf alone.
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FDA Expands Indication for Optune Device in Glioblastoma

(Medscape Medical News) Oct 6, 2015 - The US Food and Drug Administration (FDA) has expanded the indication for the Optune device (Novocare), which will allow it to be used to treat patients with newly diagnosed glioblastoma multiforme.
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USPSTF Stays the Course on Colorectal Ca Screening

(MedPage Today) Oct 5, 2015 - Screening for colorectal cancer should begin at age 50 and continue through age 75, using fecal occult blood tests (FOBT), colonoscopy, or a combination of FOBT and endoscopy, according to updated draft recommendations from the U.S Preventive Services Task Force (USPSTF).
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News Story Commentary By Academic and Community Oncologists

FDA Approves Keytruda For Advanced Non-Small Cell Lung Cancer (FDA.gov)

This is clearly an important approval, but with nivolumab already approved for squamous NSCLC and listed as a recommended...posted by: H. Jack West, MD

FDA Approves Pembrolizumab for Lung Cancer (Medscape Medical News)

This approval presents an epic problem: to obtain a companion diagnostic (pembro) or not to obtain a companion...posted by: Dean Gesme, MD

ED Induced by Prostate Biopsy Likely 'Underestimated' (Medscape Medical News)

Oncologists would do well to pose more questions of the urology community concerning ED and infections arising...posted by: Dean Gesme, MD

SHIVA - A Next-Generation Trial Disappoints, Provides Insights (Medscape Medical News)

Well darn, this is a bummer. But again I am relearning that there really is no substitute for good science. What...posted by: Thomas Marsland, MD

Information Blocking Undermining ASCO's CancerLinQ Initiative (Medscape Medical News)

So this article really goes to the heart of the matter. If any attempt at healthcare reform is to succeed, the...posted by: Thomas Marsland, MD

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